Acetyl Hexapeptide-3 (Argireline) Topical (200mg)

Acetyl Hexapeptide-3 (Argireline) topical is synthesized in the USA at 200mg per vial, with purity verified by HPLC-MS above 99%.

Current evaluation of Acetyl Hexapeptide-3 (Argireline) Topical (200mg) explores its compatibility with common formulation excipients used in cosmetic research.

Acetyl Hexapeptide-3 (Argireline) Topical (200mg) is a cosmetic-research peptide evaluated in formulations for its signaling effects on skin-related cell models.

Studies of Acetyl Hexapeptide-3 (Argireline) Topical (200mg) typically focus on collagen-related or matrix-associated endpoints in dermal cell cultures.

Each vial contains lyophilized peptide at the labeled quantity, and wholesale orders are packed in boxes of ten vials at a single per-vial price.

Quality assurance: every batch is purified by reversed-phase high-performance liquid chromatography and identity-confirmed by mass spectrometry, with purity above 99%. Lot-specific certificates of analysis are available on request. Store lyophilized vials at -20°C, protected from light and moisture; reconstitute with bacteriostatic water immediately before use and avoid repeated freeze-thaw cycles. For in-vitro laboratory research use only —not for human or veterinary use.

Research & Literature

The following peer-reviewed studies and reference documents are commonly consulted by researchers working with Acetyl Hexapeptide-3 (Argireline) Topical (200mg). Summaries are provided for orientation only and reflect the cited sources.

A synthetic hexapeptide (Argireline) with antiwrinkle activity^[1] —This study investigated the anti-wrinkle activity of the synthetic hexapeptide Argireline, also known as acetyl hexapeptide-3. The authors report that the peptide reduces wrinkle formation by interfering with SNARE-complex-mediated neurotransmitter release, an action analogous to that of botulinum toxin. They suggest that this mechanism underlies the peptide's potential as a topical cosmetic active for expression lines. (International Journal of Cosmetic Science 2002)

Investigating the effects of Argireline in a skin serum containing hyaluronic acids on skin surface wrinkles using the Visia(®) Complexion Analysis camera system for objective skin analysis^[2] —This clinical study evaluated a skin serum containing Argireline together with hyaluronic acids for its effects on facial wrinkles. Using the Visia Complexion Analysis camera system for objective measurement, the authors examined changes in skin surface parameters after treatment. The results indicated that the serum reduced visible facial wrinkles and improved aspects of skin surface quality. (GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW 2023)

Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy^[3] —This review surveys cosmeceutical peptides within the framework of the sustainable wellness economy, with particular attention to neurotransmitter-inhibitor peptides such as Argireline. The authors analyze the scientific evidence supporting anti-wrinkle claims for this peptide class. They discuss how this evidence informs the positioning of peptide-based actives in modern cosmetic development. (Frontiers in Chemistry 2020)

References

1. Blanes-Mira C, Clemente J, Jodas G, Gil A, Fernández-Ballester G, Ponsati B, Gutierrez L, Pérez-Payá E, Ferrer-Montiel A. "A synthetic hexapeptide (Argireline) with antiwrinkle activity." International Journal of Cosmetic Science. 2002. pubmed.ncbi.nlm.nih.gov/18498523/
2. Henseler H. "Investigating the effects of Argireline in a skin serum containing hyaluronic acids on skin surface wrinkles using the Visia(®) Complexion Analysis camera system for objective skin analysis." GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW. 2023. pubmed.ncbi.nlm.nih.gov/38024099/
3. Errante F, Ledwoń P, Latajka R, Rovero P, Papini AM. "Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy." Frontiers in Chemistry. 2020. public-pages-files-2025.frontiersin.org/journals/chemistry/articles/10.3389/fchem.202—

All products are supplied as lyophilized powder for in-vitro laboratory research use only and are not for human or veterinary use.