Matrixyl Topical (200mg)

Matrixyl Topical (200mg) is a lyophilized research peptide synthesized, purified, and lyophilized in the USA. Each production batch is purified by repeated rounds of reverse-phase HPLC and identity-confirmed by mass spectrometry.

Matrixyl Topical (200mg) is often screened alongside other matrix peptides to compare activity profiles in vitro.

Laboratory work on Matrixyl Topical (200mg) emphasizes controlled concentration studies and reproducible assay conditions.

Current evaluation of Matrixyl Topical (200mg) explores its compatibility with common formulation excipients used in cosmetic research.

Each vial contains lyophilized peptide at the labeled quantity, and wholesale orders are packed in boxes of ten vials at a single per-vial price.

Quality assurance: every batch is purified by reversed-phase high-performance liquid chromatography and identity-confirmed by mass spectrometry, with purity above 99%. Lot-specific certificates of analysis are available on request. Store lyophilized vials at -20°C, protected from light and moisture; reconstitute with bacteriostatic water immediately before use and avoid repeated freeze-thaw cycles. For in-vitro laboratory research use only —not for human or veterinary use.

Research & Literature

The following peer-reviewed studies and reference documents are commonly consulted by researchers working with Matrixyl Topical (200mg). Summaries are provided for orientation only and reflect the cited sources.

Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin^[1] —This controlled clinical study evaluated a topical formulation containing palmitoyl pentapeptide-4 (Matrixyl) in subjects with photoaged facial skin. The authors measured changes in the appearance of wrinkles, roughness, and other signs of photodamage. They reported improvement in these parameters, indicating that the pentapeptide may have visible benefits in photoaged skin. (International Journal of Cosmetic Science 2005)

Role of topical peptides in preventing or treating aged skin^[2] —This review summarizes clinical efficacy studies of topical peptides, including signal peptides such as palmitoyl pentapeptide-4 (Matrixyl), in aged skin. The authors examine the evidence for improvements in wrinkles and skin structure. They discuss the mechanisms proposed for these effects and the quality of the supporting clinical data. (International Journal of Cosmetic Science 2009)

Safety Assessment of Palmitoyl Oligopeptides as Used in Cosmetics^[3] —This Cosmetic Ingredient Review panel document provides a safety assessment of palmitoyl oligopeptides as used in cosmetics, including palmitoyl pentapeptide-4. The panel reviewed available data on chemistry, toxicology, and clinical exposure for these ingredients. It concluded that palmitoyl oligopeptides are safe as used in cosmetic products under the reviewed conditions. (International Journal of Toxicology 2013)

References

1. Robinson LR, Fitzgerald NC, Doughty DG, Dawes NC, Berge CA, Bissett DL. "Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin." International Journal of Cosmetic Science. 2005. pubmed.ncbi.nlm.nih.gov/18492182/
2. Gorouhi F, Maibach HI. "Role of topical peptides in preventing or treating aged skin." International Journal of Cosmetic Science. 2009. pubmed.ncbi.nlm.nih.gov/19570099/
3. Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Hill RA, Marks JG, Shank RC, Slaga TJ, Snyder PW, Johnson W, Heldreth B. "Safety Assessment of Palmitoyl Oligopeptides as Used in Cosmetics." International Journal of Toxicology. 2013. www.cir-safety.org/sites/default/files/palmit072012slr.pdf

All products are supplied as lyophilized powder for in-vitro laboratory research use only and are not for human or veterinary use.